Article
Analysis of the structural integrity of the TAP2 gene in renal cell carcinoma.
International journal of oncology - 1 Oct 2003
Hodson Isabelle, Bock Michaela, Ritz Ulrike, Brenner Walburgis, Huber Christoph, Seliger Barbara
Abstract excerpt
The transporter associated with antigen processing (TAP) gene products is involved in the processing of endogenous peptides that bind to MHC class I molecules. Mutations and/or polymorphism within these genes could alter the efficacy of the immune response which might be relevant for the development of autoimmune diseases and cancer. In this study we examined both the structural integrity and the polymorphism of...
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