Article
Association of TAP1 and TAP2 gene polymorphisms with hematological malignancies.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013
Ozbas-Gerceker Filiz, Bozman Nazli, Gezici Sevgi, Pehlivan Mustafa, Yilmaz Mehmet, Pehlivan Sacide, Oguzkan-Balci Sibel
Abstract excerpt
Transporter associated with antigen presenting (TAP) 1 and TAP2 genes are localized in the major histocompatability complex (MHC) class II region and form a heterodimer playing a key role in endogenous pathways for antigen presentation. Defects of these genes have been reported to be common in different types of cancer. Polymorphisms identified in these loci have also been investigated and reported to be...
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