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Article

Characterization of auto-regulation of the human cardiac alpha1 subunit of the L-type calcium channel: importance of the C-terminus.

Molecular and cellular biochemistry - 1 Aug 2003

Mikala Gabor, Bodi Ilona, Klockner Udo, Varadi Maria, Varadi Gyula, Koch Sheryl E, Schwartz Arnold

Abstract excerpt

The carboxyl terminal of the L-type calcium channel alpha1C subunit comprises approximately one third of the primary structure of the alpha1 subunit (> 700 amino acids residues). This region is sensitive to limited posttranslational processing. In heart and brain the alpha1C subunits are found to be truncated but the C-terminal domain remains functionally present. Based on our previous data we hypothesized that...

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PMID: 12962146
DOI: 10.1023/a:1024910605389

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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