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Article

CD40 signaling through a newly identified tumor necrosis factor receptor-associated factor 2 (TRAF2) binding site.

The Journal of biological chemistry - 14 Nov 2003

Lu Li-Fan, Cook W James, Lin Ling-Li, Noelle Randolph J

Abstract excerpt

Tumor necrosis factor receptor-associated factors (TRAFs) belong to a family of adapter proteins that are involved in tumor necrosis factor receptor superfamily signaling. It has been shown that the recruitment of TRAFs to the CD40 cytoplasmic tail is essential for CD40-mediated B cell responses. However, it has also been shown that some early B cell responses, such as up-regulation of cell surface molecules and...

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Source

Identifiers

PMID: 12960157
DOI: 10.1074/jbc.M309601200

Genes

TRAF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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