Article
Efficient allelic exchange and transposon mutagenesis in Mycobacterium avium by specialized transduction.
Applied and environmental microbiology - 1 Sept 2003
Otero Joel, Jacobs William R, Glickman Michael S
Abstract excerpt
Mycobacterium tuberculosis and Mycobacterium avium are pathogenic slow-growing mycobacteria that cause distinct human diseases. In contrast to recent advances in M. tuberculosis genetics and pathogenesis investigation, M. avium has remained genetically intractable and, consequently, its pathogenic strategies remain poorly understood. Here we report the successful development of efficient allelic exchange and...
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