Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Allelic exchange in Mycobacterium tuberculosis with long linear recombination substrates.

Journal of bacteriology - 1 Jan 1996

Balasubramanian V, Pavelka M S, Bardarov S S, Martin J, Weisbrod T R, McAdam R A, Bloom B R, Jacobs W R

Abstract excerpt

Genetic studies of Mycobacterium tuberculosis have been greatly hampered by the inability to introduce specific chromosomal mutations. Whereas the ability to perform allelic exchanges has provided a useful method of gene disruption in other organisms, in the clinically important species of mycobacteria, such as M. tuberculosis and Mycobacterium bovis, similar approaches have thus far been unsuccessful. In this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Base Sequence
Share to DNA, Bacterial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Escherichia coli

Share to Genes, Bacterial

Share to Genetic Markers

Share to Molecular Sequence Data

Share to Recombination, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 8550428
DOI: 10.1128/jb.178.1.273-279.1996
PMCID: PMC177649

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Allelic exchange in Mycobacterium tuberculosis with long linear recombination substrates.PMID 8550428Read ↗

Comparison of the construction of unmarked deletion mutations in Mycobacterium smegmatis, Mycobacterium bovis bacillus Calmette-Guérin, and Mycobacterium tuberculosis H37Rv by allelic exchange.Semantic proximity Read ↗

Allelic exchange of unmarked mutations in Mycobacterium tuberculosis.Semantic proximity Read ↗

Efficient allelic exchange and transposon mutagenesis in Mycobacterium avium by specialized transduction.Semantic proximity Read ↗

Recombination in mycobacteria.Semantic proximity Read ↗

Demonstration of allelic exchange in the slow-growing bacterium Mycobacterium avium subsp. paratuberculosis, and generation of mutants with deletions at the pknG, relA, and lsr2 loci.Semantic proximity Read ↗

Efficient method for targeted gene disruption by homologous recombination in Mycobacterium avium subspecie paratuberculosis.Semantic proximity Read ↗

Production of mutants in amino acid biosynthesis genes of Mycobacterium tuberculosis by homologous recombination.Semantic proximity Read ↗

Mycobacterial recombineering.Semantic proximity Read ↗

Specialized transduction: an efficient method for generating marked and unmarked targeted gene disruptions in Mycobacterium tuberculosis, M. bovis BCG and M. smegmatis.Semantic proximity Read ↗

Mycobacterial recombineering.Semantic proximity Read ↗

Insertional mutagenesis and illegitimate recombination in mycobacteria.Semantic proximity Read ↗

Construction of targeted mycobacterial mutants by homologous recombination.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.