Transcriptional regulation of BMP-2 activated genes in osteoblasts using gene expression microarray analysis role of DLX2 and DLX5 transcription factors

Abstract excerpt

This presentation will focus on using microarray data on a clonal osteoblast cell model to analyze the early BMP-2 responsive genes, as well as some of the later genes regulated by BMP2 during different phases of mineralization. We will focus on the early phases of gene expression that occur after BMP2 signaling from 30 min up to 1 day. The hypothesis is that understanding how these early genes are regulated...

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