Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotype discovery by gene expression profiling: mapping of biological processes linked to BMP-2-mediated osteoblast differentiation.

Journal of cellular biochemistry - 15 May 2003

Balint Eva, Lapointe David, Drissi Hicham, van der Meijden Caroline, Young Daniel W, van Wijnen Andre J, Stein Janet L, Stein Gary S, Lian Jane B

Abstract excerpt

Understanding physiological control of osteoblast differentiation necessitates characterization of the regulatory signals that initiate the events directing a cell to lineage commitment and establishing competency for bone formation. The bone morphogenetic protein, BMP-2, a member of the TGFbeta superfamily, induces osteoblast differentiation and functions through the Smad signal transduction pathway during in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Morphogenetic Protein 2
Share to Bone Morphogenetic Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Differentiation

Share to Cell Line

Share to Gene Expression Profiling

Share to Oligonucleotide Array Sequence Analysis

Share to Osteoblasts

Share to Transforming Growth Factor beta

Source

Identifiers

PMID: 12704803
DOI: 10.1002/jcb.10515

Genes

EBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotype discovery by gene expression profiling: mapping of biological processes linked to BMP-2-mediated osteoblast differentiation.PMID 12704803Read ↗

Identification of Potential Modifiers of Runx2/Cbfa1 Activity in C2C12 Cells in Response to Bone Morphogenetic Protein-7Semantic proximity Read ↗

Signaling and transcriptional regulation in osteoblast commitment and differentiationSemantic proximity Read ↗

Cell signaling and transcriptional regulation of osteoblast lineage commitment, differentiation, bone formation, and homeostasisSemantic proximity Read ↗

The Developmental Control of Osteoblast-Specific Gene Expression: Role of Specific Transcription Factors and the Extracellular Matrix EnvironmentSemantic proximity Read ↗

Development of the osteoblast phenotype: molecular mechanisms mediating osteoblast growth and differentiation.Semantic proximity Read ↗

Concepts of osteoblast growth and differentiation: basis for modulation of bone cell development and tissue formation.Semantic proximity Read ↗

Transcriptomic characterization of signaling pathways associated with osteoblastic differentiation of MC-3T3E1 cellsSemantic proximity Read ↗

HOXA10 controls osteoblastogenesis by directly activating bone regulatory and phenotypic genes.Semantic proximity Read ↗

Identification of genes responsible for osteoblast differentiation from human mesodermal progenitor cellsSemantic proximity Read ↗

A microRNA signature for a BMP2-induced osteoblast lineage commitment program.Semantic proximity Read ↗

BMP2 Commitment to the Osteogenic Lineage Involves Activation of Runx2 by DLX3 and a Homeodomain Transcriptional NetworkSemantic proximity Read ↗

Identification of Three Early Phases of Cell-Fate Determination during Osteogenic and Adipogenic Differentiation by Transcription Factor DynamicsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.