Article
Cyclic AMP response element-binding (CREB)-like proteins in a molluscan brain: cellular localization and learning-induced phosphorylation.
The European journal of neuroscience - 1 Sept 2003
Ribeiro Maria J, Serfozo Zoltán, Papp Andrea, Kemenes Ildikó, O'Shea Michael, Yin Jerry C P, Benjamin Paul R, Kemenes György
Abstract excerpt
The phosphorylation and the binding to DNA of the nuclear transcription factor, cyclic adenosine 3',5'-monophosphate (cAMP) response element-binding protein (CREB) are conserved key steps in the molecular cascade leading to the formation of long-term memory (LTM). Here, we characterize, for the first time, a CREB1-like protein in the central nervous system (CNS) of Lymnaea, a model system used widely for the...
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