Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A distinct set of Drosophila brain neurons required for neurofibromatosis type 1-dependent learning and memory.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 28 Jul 2010

Buchanan Monica E, Davis Ronald L

Abstract excerpt

Nonspecific cognitive impairments are one of the many manifestations of neurofibromatosis type 1 (NF1). A learning phenotype is also present in Drosophila melanogaster that lack a functional neurofibromin gene (nf1). Multiple studies have indicated that Nf1-dependent learning in Drosophila involves the cAMP pathway, including the demonstration of a genetic interaction between Nf1 and the rutabaga-encoded adenylyl...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenylyl Cyclases
Share to Behavior, Animal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Conditioning, Classical

Share to Memory

Share to Mushroom Bodies

Share to Neurofibromatosis 1

Share to Olfactory Pathways

Source

Open in PubMed Open full text

Identifiers

PMID: 20668197
DOI: 10.1523/JNEUROSCI.0283-10.2010
PMCID: PMC2917756

Genes

NF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A distinct set of Drosophila brain neurons required for neurofibromatosis type 1-dependent learning and memory.PMID 20668197Read ↗

A neurofibromatosis-1-regulated pathway is required for learning in Drosophila.Semantic proximity Read ↗

Preferential expression of the Drosophila rutabaga gene in mushroom bodies, neural centers for learning in insects.Semantic proximity Read ↗

Distinct functional domains of neurofibromatosis type 1 regulate immediate versus long-term memory formation.Semantic proximity Read ↗

Gilgamesh is required for rutabaga-independent olfactory learning in Drosophila.Semantic proximity Read ↗

Altered gene regulation and synaptic morphology in Drosophila learning and memory mutants.Semantic proximity Read ↗

Localization of a short-term memory in Drosophila.Semantic proximity Read ↗

Tissue-specific expression of a type I adenylyl cyclase rescues the rutabaga mutant memory defect: in search of the engram.Semantic proximity Read ↗

Induction of cAMP response element-binding protein-dependent medium-term memory by appetitive gustatory reinforcement in Drosophila larvae.Semantic proximity Read ↗

What can we teach Drosophila? What can they teach us?Semantic proximity Read ↗

The amnesiac gene product is expressed in two neurons in the Drosophila brain that are critical for memory.Semantic proximity Read ↗

Physiology and biochemistry of Drosophila learning mutants.Semantic proximity Read ↗

Olfactory learning deficits in mutants for leonardo, a Drosophila gene encoding a 14-3-3 protein.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.