Article
Plasma concentration, kinetic constants, and gene polymorphism of angiotensin I-converting enzyme in centenarians.
Clinical chemistry - 1 Oct 1998
Faure-Delanef L, Baudin B, Bénéteau-Burnat B, Beaudoin J C, Giboudeau J, Cohen D
Abstract excerpt
We have determined serum activity and kinetic constants of angiotensin I-converting enzyme (ACE), parallel to an insertion/deletion (I/D) polymorphism in its gene, in French centenarians and controls 20-70 years of age because this enzyme could have an impact on cardiovascular risk, and thus on l...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Cardiovascular Diseases
- Female
- Gene Deletion
- Genotype
- Humans
- Kinetics
- Male
- Middle Aged
- Peptidyl-Dipeptidase A
