Article
Response to combination therapy with interferon alfa-2a and ribavirin in chronic hepatitis C according to a TNF-alpha promoter polymorphism.
Digestion - 1 Jan 2003
Schiemann U, Glas J, Török P, Simperl C, Martin K, König A, Schmidt F, Schaefer M, Folwaczny C
Abstract excerpt
BACKGROUND: Tumor necrosis factor-alpha (TNF-alpha) is involved in the pathogenesis of chronic active hepatitis C. Polymorphisms in the promoter region of the TNF-alpha gene can alter the TNF-alpha expression and modify the host immune response. The present study aimed at the correlation of the G...
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