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Article

TNFA -308G>A and IL10 -1082A>G polymorphisms seem to be predictive biomarkers of chronic HCV infection.

BMC infectious diseases - 3 Nov 2021

Santiago Angélica Menezes, da Silva Graça Amoras Ednelza, Queiroz Maria Alice Freitas, da Silva Conde Simone Regina Souza, Cayres-Vallinoto Izaura Maria Vieira, Ishak Ricardo, Vallinoto Antonio Carlos Rosário

Abstract excerpt

BACKGROUND: Genetic changes may induce dysregulated cytokine production and affect the progression of the chronic disease caused by the hepacivirus C (HCV) because the balance of pro- and anti-inflammatory cytokines determines the outcome of infection. This study evaluated the TNFA -308G>A and IL10 -1082A>G polymorphisms in the susceptibility and progress of chronic hepatitis C. METHOD: The study included 101...

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Identifiers

PMID: 34732154
DOI: 10.1186/s12879-021-06835-9
PMCID: PMC8567538

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