Article
Jumping the barrier to beta-lactam resistance in Staphylococcus aureus.
Journal of bacteriology - 1 Sept 2003
Katayama Yuki, Zhang Hong-Zhong, Hong Dong, Chambers Henry F
Abstract excerpt
Although the staphylococcal methicillin resistance determinant, mecA, resides on a mobile genetic element, staphylococcus cassette chromosome mec (SCCmec), its distribution in nature is limited to as few as five clusters of related methicillin-resistant Staphylococcus aureus (MRSA) clones. To investigate the potential role of the host chromosome in clonal restriction of the methicillin resistance determinant, we...
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