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Genetic Background Affects Stability of mecA in Staphylococcus aureus

1 May 2005

Abstract excerpt

The staphylococcal methicillin resistance determinant, mecA, resides on a mobile genetic element, staphylococcus chromosomal cassette mec (SCCmec). The distribution of SCCmec in nature is limited to relatively few clonal complexes of related methicillin-resistant Staphylococcus aureus (MRSA). We have previously reported that some genetic backgrounds are restrictive of mecA and penicillin-binding protein 2a...

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PMID: 15872270
DOI: 10.1128/jcm.43.5.2380-2383.2005

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