Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SmcR and cyclic AMP receptor protein coactivate Vibrio vulnificus vvpE encoding elastase through the RpoS-dependent promoter in a synergistic manner.

The Journal of biological chemistry - 14 Nov 2003

Jeong Hye Sook, Lee Myoung Hee, Lee Kyu-Ho, Park Soon-Jung, Choi Sang Ho

Abstract excerpt

The putative virulence factors of Vibrio vulnificus include an elastase, the gene product of vvpE. We previously demonstrated that vvpE expression is differentially directed by two different promoters in a growth phase-dependent manner. The activity of the stationaryphase promoter (promoter S (PS)) is dependent on RpoS and is also under the positive control of cyclic AMP receptor protein (CRP). In this study,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Northern
Share to Cyclic AMP Receptor Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Deoxyribonuclease I

Share to Gene Expression Regulation, Bacterial

Share to Pancreatic Elastase

Share to Sigma Factor

Share to Trans-Activators

Share to Vibrio vulnificus

Source

Identifiers

PMID: 12947096
DOI: 10.1074/jbc.M308184200

Genes

CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SmcR and cyclic AMP receptor protein coactivate Vibrio vulnificus vvpE encoding elastase through the RpoS-dependent promoter in a synergistic manner.PMID 12947096Read ↗

Differential expression of Vibrio vulnificus elastase gene in a growth phase-dependent manner by two different types of promoters.Semantic proximity Read ↗

Transcriptional regulatory cascade for elastase production in Vibrio vulnificus: LuxO activates luxT expression and LuxT represses smcR expression.Semantic proximity Read ↗

LuxR homologue SmcR is essential for Vibrio vulnificus pathogenesis and biofilm detachment, and its expression is induced by host cells.Semantic proximity Read ↗

Repression of virulence genes by phosphorylation‐dependent oligomerization ofCsrR at target promoters in <i>S. pyogenes</i>Semantic proximity Read ↗

Vibrio vulnificus rpoS expression is repressed by direct binding of cAMP-cAMP receptor protein complex to its two promoter regions.Semantic proximity Read ↗

Analysis of gene expression in mouse alveolar macrophages stimulated with quorum-sensing mutants of Vibrio vulnificus.Semantic proximity Read ↗

The DNA binding domain of the Vibrio vulnificus SmcR transcription factor is flexible and binds diverse DNA sequences.Semantic proximity Read ↗

ppGpp with DksA controls gene expression in the locus of enterocyte effacement (LEE) pathogenicity island of enterohaemorrhagic Escherichia coli through activation of two virulence regulatory genesSemantic proximity Read ↗

RbsR Activates Capsule but Represses the rbsUDK Operon in Staphylococcus aureusSemantic proximity Read ↗

Identification and functional analysis of vibrio vulnificus SmcR, a novel global regulator.Semantic proximity Read ↗

SmcR-dependent regulation of adaptive phenotypes in Vibrio vulnificus.Semantic proximity Read ↗

Synthesis of group A streptococcal virulence factors is controlled by a regulatory RNA molecule.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.