Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptional regulatory cascade for elastase production in Vibrio vulnificus: LuxO activates luxT expression and LuxT represses smcR expression.

The Journal of biological chemistry - 17 Nov 2006

Roh Jong-Bok, Lee Mi-Ae, Lee Hyun-Jung, Kim Sung-Min, Cho Yona, Kim You-Jin, Seok Yeong-Jae, Park Soon-Jung, Lee Kyu-Ho

Abstract excerpt

Vibrio vulnificus causes diseases through actions of various virulence factors, including the elastase encoded by the vvpE gene. Through transposon mutagenesis of V. vulnificus, vvpE expression was shown to be increased by luxO mutation. Since the vvpE gene is known to be positively regulated by SmcR via direct binding to the vvpE promoter, the role of LuxO in smcR expression was investigated. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to DNA-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Bacterial

Share to Pancreatic Elastase

Share to Repressor Proteins

Share to Trans-Activators

Share to Transcription, Genetic

Share to Vibrio vulnificus

Source

Identifiers

PMID: 16971386
DOI: 10.1074/jbc.M607844200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptional regulatory cascade for elastase production in Vibrio vulnificus: LuxO activates luxT expression and LuxT represses smcR expression.PMID 16971386Read ↗

LuxR homologue SmcR is essential for Vibrio vulnificus pathogenesis and biofilm detachment, and its expression is induced by host cells.Semantic proximity Read ↗

SmcR and cyclic AMP receptor protein coactivate Vibrio vulnificus vvpE encoding elastase through the RpoS-dependent promoter in a synergistic manner.Semantic proximity Read ↗

Analysis of gene expression in mouse alveolar macrophages stimulated with quorum-sensing mutants of Vibrio vulnificus.Semantic proximity Read ↗

Identification and functional analysis of vibrio vulnificus SmcR, a novel global regulator.Semantic proximity Read ↗

Differential expression of Vibrio vulnificus elastase gene in a growth phase-dependent manner by two different types of promoters.Semantic proximity Read ↗

Phenotypic Discovery of an Antivirulence Agent against Vibrio vulnificus via Modulation of Quorum-Sensing Regulator SmcR.Semantic proximity Read ↗

The DNA binding domain of the <i>Vibrio vulnificus</i> SmcR transcription factor is flexible and recognizes diverse DNA sequencesSemantic proximity Read ↗

LuxO controls extracellular protease, haemolytic activities and siderophore production in fish pathogen Vibrio alginolyticus.Semantic proximity Read ↗

Repression of virulence genes by phosphorylation‐dependent oligomerization ofCsrR at target promoters in <i>S. pyogenes</i>Semantic proximity Read ↗

The DNA binding domain of the Vibrio vulnificus SmcR transcription factor is flexible and binds diverse DNA sequences.Semantic proximity Read ↗

Regulation of metalloprotease gene expression in Vibrio vulnificus by a Vibrio harveyi LuxR homologue.Semantic proximity Read ↗

Iron facilitates the RetS-Gac-Rsm cascade to inversely regulate protease IV (piv) expression via the sigma factor PvdS in Pseudomonas aeruginosa.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.