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Article

LuxR homologue SmcR is essential for Vibrio vulnificus pathogenesis and biofilm detachment, and its expression is induced by host cells.

Infection and immunity - 1 Oct 2013

Kim Seung Min, Park Jin Hwan, Lee Hyun Sung, Kim Won Bin, Ryu Jung Min, Han Ho Jae, Choi Sang Ho

Abstract excerpt

Quorum sensing is a cell-to-cell communication system known to control many bacterial processes. In the present study, the functions of quorum sensing in the pathogenesis of Vibrio vulnificus, a food-borne pathogen, were assessed by evaluating the virulence of a mutant deficient in SmcR, a quorum-sensing regulator and homologue of LuxR. When biofilms were used as an inoculum, the smcR mutant was impaired in...

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Identifiers

PMID: 23897607
DOI: 10.1128/IAI.00561-13
PMCID: PMC3811769

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