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Article

The Role of C/EBPε in the Terminal Stages of Granulocyte Differentiation

1 Mar 2001

Abstract excerpt

As a consequence of its characterization using both in vitro and knockout mouse models, the myeloid-specific transcription factor, CCAAT/enhancer binding protein (C/EBP)epsilon, has been identified as a critical regulator of terminal granulopoiesis and one of the causative mutations in the human disease, neutrophil-specific granule deficiency. C/EBPs are a family of transcription factors sharing numerous...

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PMID: 11239167
DOI: 10.1634/stemcells.19-2-125

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