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Differential Expression of Vascular Endothelial Growth Factor–A Isoforms at Different Stages of Melanoma Progression

1 Sept 2003

Abstract excerpt

Vascular endothelial growth factor-A (VEGF-A) is an important mediator of angiogenesis in normal and neoplastic tissues. Total VEGF-A levels have been associated with melanoma progression, but the relative contributions of each isoform is unknown. To determine whether differences in the production of any or all of the major VEGF-A isoforms are related to stage of progression, we compared message levels for the...

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PMID: 12946796
DOI: 10.1016/s1072-7515(03)00388-0

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