Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Apparently normal tumor necrosis factor receptor 1 signaling in the absence of the silencer of death domains.

Molecular and cellular biology - 1 Sept 2003

Endres Robert, Häcker Georg, Brosch Inge, Pfeffer Klaus

Abstract excerpt

The silencer of death domains (SODD) has been proposed to prevent constitutive signaling of tumor necrosis factor receptor 1 (TNFR1) in the absence of ligand. Besides TNFR1, death receptor 3 (DR3), Hsp70/Hsc70, and Bcl-2 have been characterized as binding partners of SODD. In order to investigate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dose-Response Relationship, Immunologic
Share to JNK Mitogen-Activated Protein Kinases
Share to Listeria

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lymphocyte Subsets

Share to Mitogen-Activated Protein Kinase 3

Share to Receptors, Tumor Necrosis Factor

Share to Receptors, Tumor Necrosis Factor, Type I

Share to Staurosporine

Source

Open in PubMed Open full text

Identifiers

PMID: 12944486
DOI: 10.1128/MCB.23.18.6609-6617.2003
PMCID: PMC193695

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12944486-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Apparently normal tumor necrosis factor receptor 1 signaling in the absence of the silencer of death domains.PMID 12944486Read ↗

Prevention of constitutive TNF receptor 1 signaling by silencer of death domains.Semantic proximity Read ↗

Phenotypic analysis of TNFR1-deficient mice and characterization of TNFR1-deficient fibroblasts in vitro.Semantic proximity Read ↗

Lipopolysaccharide and D-galactosamine-induced hepatic injury is mediated by TNF-alpha and not by Fas ligand.Semantic proximity Read ↗

Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes.Semantic proximity Read ↗

Cytokine knockout mice: possible application in toxicological research.Semantic proximity Read ↗

The intriguing biology of the tumour necrosis factor/tumour necrosis factor receptor superfamily: players, rules and the gamesSemantic proximity Read ↗

Regulated necrosis: disease relevance and therapeutic opportunitiesSemantic proximity Read ↗

TNFR1 is essential for CD40, but not for lipopolysaccharide-induced sickness behavior and clock gene dysregulationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.