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Article

Cytokine knockout mice: possible application in toxicological research.

Toxicology - 20 Dec 1995

Ryffel B

Abstract excerpt

Knockout mice obtained by homologous recombination technology may be valuable tools for in vivo investigations in toxico-pathogenesis. A short review of the phenotype of mice with distinct cytokine deletions, which occur either naturally or are obtained by homologous recombination, is given. The...

Topics

Animals
Autoimmune Diseases
Cytokines
Hematopoiesis
Kidney
Liver
Mice
Mice, Knockout
Phenotype
Shock, Septic

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8638285
DOI: 10.1016/0300-483x(95)03126-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8638285-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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