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Article

Familial/sporadic glucocorticoid resistance: clinical phenotype and molecular mechanisms.

Annals of the New York Academy of Sciences - 1 Jun 2004

Charmandari Evangelia, Kino Tomoshige, Chrousos George P

Abstract excerpt

Glucocorticoids regulate a variety of biologic processes and exert profound influences on many physiologic functions. Their actions are mediated by the glucocorticoid receptor (GR), which belongs to the nuclear receptor family of ligand-dependent transcription factors. Alterations in tissue sensitivity to glucocorticoids may manifest as states of resistance or hypersensitivity. Glucocorticoid resistance is a...

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Identifiers

PMID: 15265781
DOI: 10.1196/annals.1321.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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