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Article

Influence of pharmacogenetic factors on Alzheimer's disease therapeutics.

Neuro-degenerative diseases - 1 Jan 2008

Cacabelos Ramón

Abstract excerpt

Alzheimer's disease (AD) is the result of the phenotypic expression of more than 200 genes which are potentially involved in neurodegeneration. Structural and functional genomics studies demonstrate that genomic factors, probably induced by environmental factors, cerebrovascular dysfunction, and epigenetic phenomena, might be responsible for AD pathogenesis leading to premature neuronal death. Drug metabolism,...

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PMID: 18322383
DOI: 10.1159/000113695

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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