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ITCH E3 Ubiquitin Ligase Interacts with Ebola Virus VP40 To Regulate Budding

4 Aug 2016

Abstract excerpt

UNLABELLED: Ebola virus (EBOV) and Marburg virus (MARV) belong to the Filoviridae family and can cause outbreaks of severe hemorrhagic fever, with high mortality rates in humans. The EBOV VP40 (eVP40) and MARV VP40 (mVP40) matrix proteins play a central role in virion assembly and egress, such that independent expression of VP40 leads to the production and egress of virus-like particles (VLPs) that accurately...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 27489272
DOI: 10.1128/jvi.01078-16

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Research trail→

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ITCH E3 Ubiquitin Ligase Interacts with Ebola Virus VP40 To Regulate BuddingPMID 27489272Read ↗

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