Article
A role for septins in cellular and axonal migration in C. elegans.
Developmental biology - 1 Sept 2003
Finger Fern P, Kopish Kevin R, White John G
Abstract excerpt
Caenorhabditis elegans has two genes, unc-59 and unc-61, encoding septin-family GTPases. Mutations in the septin genes cause defects in locomotory behavior that have been previously attributed to cytokinesis failures in postembryonic neuroblasts. We find that mutations in either septin gene frequently cause uncoordination in newly hatched larvae in the absence of cytokinesis failures. The septins exhibit...
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