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Article

High frequency of MYH gene mutations in a subset of patients with familial adenomatous polyposis.

Gastroenterology - 1 Jun 2004

Venesio Tiziana, Molatore Sara, Cattaneo Francesca, Arrigoni Arrigo, Risio Mauro, Ranzani Guglielmina N

Abstract excerpt

BACKGROUND & AIMS: Inherited colorectal polyposis has been linked to constitutive mutations of the APC tumor suppressor gene. Recently, germline mutations in the base excision repair gene MYH have been associated with a recessively inherited form of the disease. The aim of this study was to evaluate germline mutation frequencies of both MYH and APC susceptibility genes in Italian patients with attenuated familial...

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Source

Identifiers

PMID: 15188161
DOI: 10.1053/j.gastro.2004.02.022

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APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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