Article
Nicotinamide ribosyl uptake mutants in Haemophilus influenzae.
Infection and immunity - 1 Sept 2003
Herbert Mark, Sauer Elizabeta, Smethurst Graeme, Kraiss Anita, Hilpert Anna-Karina, Reidl Joachim
Abstract excerpt
The gene for the nicotinamide riboside (NR) transporter (pnuC) was identified in Haemophilus influenzae. A pnuC mutant had only residual NR uptake and could survive in vitro with high concentrations of NR, but could not survive in vivo. PnuC may represent a target for the development of inhibitor...
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