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Article

Is a NAD pyrophosphatase activity necessary for Haemophilus influenzae type b multiplication in the blood stream?

International journal of medical microbiology : IJMM - 1 Aug 2001

Schmidt-Brauns J, Herbert M, Kemmer G, Kraiss A, Schlör S, Reidl J

Abstract excerpt

Haemophilus influenzae has an absolute requirement for factor V because it lacks all the biosynthetic enzymes necessary for the de novo synthesis of NAD. Factor V can be provided as either nicotinamide adenosine dinucleotide (NAD), nicotinamide mono-nucleotide (NMN) or nicotinamide riboside (NR) in vitro, but little is known about the source or the mechanism of uptake for factor V in vivo. Recently, a...

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PMID: 11554562
DOI: 10.1078/1438-4221-00122

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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