Article
Quantitative analysis of bristle number in Drosophila mutants identifies genes involved in neural development.
Current biology : CB - 19 Aug 2003
Norga Koenraad K, Gurganus Marjorie C, Dilda Christy L, Yamamoto Akihiko, Lyman Richard F, Patel Prajal H, Rubin Gerald M, Hoskins Roger A, Mackay Trudy F, Bellen Hugo J
Abstract excerpt
BACKGROUND: The identification of the function of all genes that contribute to specific biological processes and complex traits is one of the major challenges in the postgenomic era. One approach is to employ forward genetic screens in genetically tractable model organisms. In Drosophila melanogaster, P element-mediated insertional mutagenesis is a versatile tool for the dissection of molecular pathways, and...
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