Article
Drosophila bristles and the nature of quantitative genetic variation.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 29 Jul 2005
Mackay Trudy F, Lyman Richard F
Abstract excerpt
Numbers of Drosophila sensory bristles present an ideal model system to elucidate the genetic basis of variation for quantitative traits. Here, we review recent evidence that the genetic architecture of variation for bristle numbers is surprisingly complex. A substantial fraction of the Drosophila genome affects bristle number, indicating pervasive pleiotropy of genes that affect quantitative traits. Further, a...
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