Article
Identification of candidate genes that underlie the QTL on chromosome 1 that mediates genetic differences in stress-ethanol interactions.
Physiological genomics - 1 Aug 2015
Cook Melloni N, Baker Jessica A, Heldt Scott A, Williams Robert W, Hamre Kristin M, Lu Lu
Abstract excerpt
Alcoholism, stress, and anxiety are strongly interacting heritable, polygenetic traits. In a previous study, we identified a quantitative trait locus (QTL) on murine chromosome (Chr) 1 between 23.0 and 31.5 Mb that modulates genetic differences in the effects of ethanol on anxiety-related phenotypes. The goal of the present study was to extend the analysis of this locus with a focus on identifying candidate genes...
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