Article
[Mutation analysis on MSH2 and MLH1 genes in patients of colorectal cancer at early age].
Zhonghua yi xue za zhi - 10 Aug 2003
Wang Ya-ping, Zhang Jun-ni, Li Jin-tian, Zhou Jian-nong, Zhang Xiao-mei, Zhu Ming
Abstract excerpt
OBJECTIVE: To investigate the etiological role of function and construction alteration in mismatch repair genes MSH2 and MLH1 in the patients onset of colorectal cancers (CRC) at early ages. METHODS: The genomic DNA was extracted from the tumor tissues and normal colon tissues during operation an...
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