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Article

[Mutation analysis on MSH2 and MLH1 genes in patients of colorectal cancer at early age].

Zhonghua yi xue za zhi - 10 Aug 2003

Wang Ya-ping, Zhang Jun-ni, Li Jin-tian, Zhou Jian-nong, Zhang Xiao-mei, Zhu Ming

Abstract excerpt

OBJECTIVE: To investigate the etiological role of function and construction alteration in mismatch repair genes MSH2 and MLH1 in the patients onset of colorectal cancers (CRC) at early ages. METHODS: The genomic DNA was extracted from the tumor tissues and normal colon tissues during operation and subjected to analysis of microsatellite instability (MSI) in 42 Chinese patients aged less than 50 with CRC. Mutation...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12930688

Genes

MLH1
MSH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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