Article
Meta-analysis of MSH6 gene mutation frequency in colorectal and endometrial cancers.
Journal of toxicology and environmental health. Part A - 1 Jan 2009
Zhao Ya-shuang, Hu Fu-lan, Wang Fan, Han Bing, Li Dan-dan, Li Xiang-wei, Zhu Sui
Abstract excerpt
Studies on mutations and mutation frequencies of the MSH6 gene, which mainly focus on new types of mutations in small samples, have been published ever since the first report of MSH6 mutation in two atypical hereditary non-polyposis colorectal cancer patients. However, the results remain inconsistent. Therefore, a systematic review was conducted and a meta-analysis was undertaken to determine the frequency of...
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