Article
Novel case-control test in a founder population identifies P-selectin as an atopy-susceptibility locus.
American journal of human genetics - 1 Sept 2003
Bourgain Catherine, Hoffjan Sabine, Nicolae Raluca, Newman Dina, Steiner Lori, Walker Karen, Reynolds Rebecca, Ober Carole, McPeek Mary Sara
Abstract excerpt
To avoid problems related to unknown population substructure, association studies may be conducted in founder populations. In such populations, however, the relatedness among individuals may be considerable. Neglecting such correlations among individuals can lead to seriously spurious association...
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