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Article

A strategy analysis for genetic association studies with known inbreeding.

BMC genetics - 18 Jul 2011

Cabras Stefano, Castellanos Maria Eugenia, Biino Ginevra, Persico Ivana, Sassu Alessandro, Casula Laura, Del Giacco Stefano, Bertolino Francesco, Pirastu Mario, Pirastu Nicola

Abstract excerpt

BACKGROUND: Association studies consist in identifying the genetic variants which are related to a specific disease through the use of statistical multiple hypothesis testing or segregation analysis in pedigrees. This type of studies has been very successful in the case of Mendelian monogenic disorders while it has been less successful in identifying genetic variants related to complex diseases where the...

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PMID: 21767363
DOI: 10.1186/1471-2156-12-63
PMCID: PMC3155486

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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