Article
Multilocus linkage disequilibrium mapping by the decay of haplotype sharing with samples of related individuals.
Genetic epidemiology - 1 Sept 2005
Zhang Jian, Schneider Daniel, Ober Carole, McPeek Mary Sara
Abstract excerpt
We consider the problem of multilocus linkage disequilibrium (LD) mapping of a trait-associated variant from case-control samples in which some individuals may be related. Our method, which we call DHS-R, is an extension of the decay of haplotype sharing (DHS) method of McPeek and Strahs and Strahs and McPeek. The DHS-R method shares the main features of the DHS method: (1) it allows construction of a confidence...
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