Article
Chondroitin sulfate proteoglycans are required for lung growth and morphogenesis in vitro.
American journal of physiology. Lung cellular and molecular physiology - 1 Dec 2003
Shannon John M, McCormick-Shannon Kathleen, Burhans Michael S, Shangguan Xiaofei, Srivastava Kalpana, Hyatt Brian A
Abstract excerpt
Proteoglycans (PGs) have been shown to play a key role in the development of many tissues. We have investigated the role of sulfated PGs in early rat lung development by treating cultured tissues with 30 mM sodium chlorate, a global inhibitor of PG sulfation. Chlorate treatment disrupted growth a...
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