Article
[Allelic polymorphism of endothelial NO-synthase (T(-786)-->C) promoter gene as risk factor of acute coronary syndrome].
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) - 1 Jan 2005
Dosenko V Ie, Zahoriĭ V Iu, Lutaĭ Ia M, Parkhomenko O M, Moĭbenko O O
Abstract excerpt
Frequency of promoter endothelial NO-synthase gene allelic polymorphism by using polymerase chain reaction and restriction fragment length polymorphism (RFLP-PCR) was determined in 221 patients with acute coronary syndrome (ACS) and in 83 almost healthy subjects. Data obtained indicate that different promoter allelic variant frequency differs significantly in patients with ACS and in control group. Correlation of...
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