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Article

Activation-independent parathyroid hormone receptor internalization is regulated by NHERF1 (EBP50).

The Journal of biological chemistry - 31 Oct 2003

Sneddon W Bruce, Syme Colin A, Bisello Alessandro, Magyar Clara E, Rochdi Moulay Driss, Parent Jean-Luc, Weinman Edward J, Abou-Samra Abdul B, Friedman Peter A

Abstract excerpt

Parathyroid hormone (PTH) regulates extracellular calcium homeostasis through the type 1 PTH receptor (PTH1R) expressed in kidney and bone. The PTH1R undergoes beta-arrestin/dynamin-mediated endocytosis in response to the biologically active forms of PTH, PTH-(1-34), and PTH-(1-84). We now show t...

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Source

Identifiers

PMID: 12920119
DOI: 10.1074/jbc.M306019200

Genes

NHERF1
PTH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12920119-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Activation-independent parathyroid hormone receptor internalization is regulated by NHERF1 (EBP50).PMID 12920119Read ↗

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