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Article

Internalization determinants of the parathyroid hormone receptor differentially regulate beta-arrestin/receptor association.

The Journal of biological chemistry - 8 Mar 2002

Vilardaga Jean-Pierre, Krasel Cornelius, Chauvin Stéphanie, Bambino Tom, Lohse Martin J, Nissenson Robert A

Abstract excerpt

beta-Arrestins have been implicated in regulating internalization of the parathyroid hormone receptor (PTHR), but the structural features in the receptor required for this effect are unknown. In the present study performed in HEK-293 cells, we demonstrated that different topological domains of PTHR are implicated in agonist-dependent receptor internalization; truncation of the cytoplasmic tail (PTHR-TR),...

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PMID: 11726668
DOI: 10.1074/jbc.M110433200

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PTH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Internalization determinants of the parathyroid hormone receptor differentially regulate beta-arrestin/receptor association.PMID 11726668Read ↗

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