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Article

Involvement of the C-terminal disulfide-bonded loop of murine leukemia virus SU protein in a postbinding step critical for viral entry.

Journal of virology - 1 Jun 2005

Burkhart Michael D, D'Agostino Paul, Kayman Samuel C, Pinter Abraham

Abstract excerpt

A role for the C-terminal domain (CTD) of murine leukemia virus (MuLV) Env protein in viral fusion was indicated by the potent inhibition of MuLV-induced fusion, but not receptor binding, by two rat monoclonal antibodies (MAbs) specific for epitopes in the CTD. Although these two MAbs, 35/56 and 83A25, have very different patterns of reactivity with viral isolates, determinants of both epitopes were mapped to the...

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Identifiers

PMID: 15919941
DOI: 10.1128/JVI.79.12.7868-7876.2005
PMCID: PMC1143666

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Source receipt: pubmed, retrieved 7 Sept 2026.

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