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Article

Analysis of a temperature-sensitive mutation affecting the integration protein of Moloney murine leukemia virus.

Virology - 1 Feb 1993

Schwartzberg P L, Roth M J, Tanese N, Goff S P

Abstract excerpt

We have previously described a series of mutations in the 3' terminus of the pol gene of Moloney murine leukemia virus which adversely affect the establishment of an integrated provirus (Roth, M. J., Schwartzberg, P., Tanese, N., and Goff, S. P., J. Virol. 64, 4709-4717, 1990). While most of the mutations were unconditionally lethal for virus replication, we now demonstrate that one mutation, in6161-12, a 12-base...

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Identifiers

PMID: 8421906
DOI: 10.1006/viro.1993.1086

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