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Article

U1 snRNP-dependent function of TIAR in the regulation of alternative RNA processing of the human calcitonin/CGRP pre-mRNA.

Molecular and cellular biology - 1 Sept 2003

Zhu Hui, Hasman Robert A, Young Katherine M, Kedersha Nancy L, Lou Hua

Abstract excerpt

Alternative RNA processing of human calcitonin/CGRP pre-mRNA is regulated by an intronic enhancer element. Previous studies have demonstrated that multiple sequence motifs within the enhancer and a number of trans-acting factors play critical roles in the regulation. Here, we report the identification of TIAR as a novel player in the regulation of human calcitonin/CGRP alternative RNA processing. TIAR binds to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Enhancer Elements, Genetic

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Share to Ribonucleoprotein, U1 Small Nuclear

Share to Ribonucleoprotein, U4-U6 Small Nuclear

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Source

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Identifiers

PMID: 12917321
DOI: 10.1128/MCB.23.17.5959-5971.2003
PMCID: PMC180986

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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