Uridine branch acceptor is a cis-acting element involved in regulation of the alternative processing of calcitonin/CGRP-l pre-mRNA.

doi:10.1093/nar/18.18.5365

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Article

Uridine branch acceptor is a cis-acting element involved in regulation of the alternative processing of calcitonin/CGRP-l pre-mRNA.

Nucleic acids research - 25 Sept 1990

Adema G J, van Hulst K L, Baas P D

Abstract excerpt

The human calcitonin/CGRP-I (CALC-I) gene contains 6 exons and encodes two polypeptide precursors. In thyroid C-cells, calcitonin (CT) mRNA is produced by splicing of exons 1-2-3 to exon 4 (CT-encoding) and polyadenylation at exon 4. CGRP-I mRNA is produced in particular neural cells by splicing...

Topics

Adenosine
Base Sequence
Blotting, Northern
Calcitonin
Calcitonin Gene-Related Peptide
Exons
Genes
Humans
Molecular Sequence Data
Mutation
RNA Precursors
RNA Splicing
Uridine

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