Article
Interaction between vitamin D receptor genotype and estrogen receptor alpha genotype influences vertebral fracture risk.
The Journal of clinical endocrinology and metabolism - 1 Aug 2003
Colin E M, Uitterlinden A G, Meurs J B J, Bergink A P, van de Klift M, Fang Y, Arp P P, Hofman A, van Leeuwen J P T M, Pols H A P
Abstract excerpt
In view of the interactions of vitamin D and the estrogen endocrine system, we studied the combined influence of polymorphisms in the estrogen receptor (ER) alpha gene and the vitamin D receptor (VDR) gene on the susceptibility to osteoporotic vertebral fractures in 634 women aged 55 yr and older. Three VDR haplotypes (1, 2, and 3) of the BsmI, ApaI, and TaqI restriction fragment length polymorphisms and three...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.