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Article

Association of Vitamin D Receptor (VDR) Gene Polymorphisms with Osteoporotic Vertebral Fracture Risk: A Case-Control Study.

Genes - 31 Mar 2026

Durmuş Nimetullah Alper, Orunoglu Merdan, Oral Sukru, Koç Rahmi Kemal, Dundar Munis, Meral Mehmet

Abstract excerpt

BACKGROUND/OBJECTIVES: Osteoporosis is a systemic skeletal disorder characterized by reduced bone mass and microarchitectural deterioration, resulting in an increased risk of fragility fractures, particularly vertebral fractures. Genetic factors are considered important in osteoporotic fracture susceptibility, and polymorphisms of the vitamin D receptor (VDR) gene have been widely studied because of their role in...

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Identifiers

PMID: 42074527
DOI: 10.3390/genes17040410
PMCID: PMC13116875

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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