Article
Vitamin D receptor gene and risk of fracture in postmenopausal women: a meta-analysis.
Climacteric : the journal of the International Menopause Society - 1 Aug 2014
Shen H, Xie J, Lu H
Abstract excerpt
OBJECTIVE: Fracture is the major clinical outcome of osteoporosis. The vitamin D receptor (VDR) gene is thought to be a candidate gene for osteoporosis. Many genetic studies have suggested an association of VDR polymorphisms and fracture risk, but evidence remains conflicting. The aim of this study was to evaluate the genetic effect of the BsmI, TaqI, ApaI and FokI polymorphisms in the VDR gene on fracture risk...
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