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Article

HBV Core Particles as a Carrier for B Cell/T Cell Epitopes

1 Jan 2001

Abstract excerpt

In the middle 80s, recombinant hepatitis B virus cores (HBc) gave onset to icosahedral virus-like particles (VLPs) as a basic class of non-infectious carriers of foreign immunological epitopes. The recombinant HBc particles were used to display immunodominant epitopes of hepatitis B, C, and E virus, human rhinovirus, papillomavirus, hantavirus, and influenza virus, human and simian immunodeficiency virus, bovine...

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PMID: 11509871
DOI: 10.1159/000050037

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