Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detection of UGT1A10 polymorphisms and their association with orolaryngeal carcinoma risk.

Cancer - 15 Aug 2003

Elahi Abul, Bendaly Jean, Zheng Zhong, Muscat Joshua E, Richie John P, Schantz Stimson P, Lazarus Philip

Abstract excerpt

BACKGROUND: UGT1A10 exhibits glucuronidating activity against metabolites of the tobacco smoke carcinogen, benzo(a)pyrene, and is expressed highly in numerous target tissues for tobacco-related cancers including the upper aerodigestive tract. The current study was conducted to determine the prevalence of genetic polymorphisms in the UGT1A10-specific region of the UDP-glucuronosyltransferase family 1A locus and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcohol Drinking
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glucuronosyltransferase

Share to Laryngeal Neoplasms

Share to Mouth Neoplasms

Share to Odds Ratio

Share to Racial Groups

Share to Smoking

Source

Identifiers

PMID: 12910533
DOI: 10.1002/cncr.11587

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detection of UGT1A10 polymorphisms and their association with orolaryngeal carcinoma risk.PMID 12910533Read ↗

UDP-glucuronosyltransferase 1A10: activity against the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, and a potential role for a novel UGT1A10 promoter deletion polymorphism in cancer susceptibility.Semantic proximity Read ↗

Tobacco carcinogen-detoxifying enzyme UGT1A7 and its association with orolaryngeal cancer risk.Semantic proximity Read ↗

Functional characterization of low-prevalence missense polymorphisms in the UDP-glucuronosyltransferase 1A9 gene.Semantic proximity Read ↗

Cytochrome P450 1A1 Ile462Val polymorphism and oral carcinoma risk: an updated meta-analysis including 1,515 cases and 2,233 controls.Semantic proximity Read ↗

Polymorphisms of the carcinogen detoxifying UDP-glucuronosyltransferase UGT1A7 in proximal digestive tract cancer.Semantic proximity Read ↗

Genetic polymorphisms in head and neck cancer riskSemantic proximity Read ↗

Identification of a prevalent functional missense polymorphism in the UGT2B10 gene and its association with UGT2B10 inactivation against tobacco-specific nitrosamines.Semantic proximity Read ↗

UGT1A and UGT2B genetic variation alters nicotine and nitrosamine glucuronidation in european and african american smokers.Semantic proximity Read ↗

Characterization of UDP-glucuronosyltransferase 2A1 (UGT2A1) variants and their potential role in tobacco carcinogenesis.Semantic proximity Read ↗

Analysis of rs1048943 in the CYP1A1 gene in laryngeal cancer - a case control studySemantic proximity Read ↗

Polymorphisms of uridine-diphosphoglucuronosyltransferase 1A7 gene in Taiwan Chinese.Semantic proximity Read ↗

CYP1A1 and CYP1B1 polymorphisms and risk of lung cancer among never smokers: a population-based study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.